Science Links Japan | Mercury and Atopic Dermatitis. An Epidemiological Study of the Influence of Dental Amalgam on the Development of Atopic Dermatitis in Children.

Mercury and Atopic Dermatitis. An Epidemiological Study of the Influence of Dental Amalgam on the Development of Atopic Dermatitis in Children.

Accession number;01A0174051

Title;Mercury and Atopic Dermatitis. An Epidemiological Study of the Influence of Dental Amalgam on the Development of Atopic Dermatitis in Children.

Author; SHIMAZU(KODERA) TSUNETOSHI (Shimazuiin)

Journal Title;Skin Research

Journal Code:Z0014B

ISSN:0018-1390

VOL.42;NO.Suppl.22;PAGE.15-21(2000)

Figure&Table&Reference;FIG.13, TBL.1, REF.24

Pub. Country;Japan

Language;Japanese

Abstract;The influence of dental amalgam fillings on the prevalence of atopic dermatitis (AD) was studied in elementary school students. 98 of 256 students, or 38.0%, had been treated with dental silver fillings, or amalgam, prior to our examination. 59 of the 256 students, or 23.0%, were suffering from AD. The prevalence of AD in the amalgam treated students was 48.0% and 7.6% in the students without amalgam treatment. The amalgam treated students showed a higher prevalence of AD as compared to the students without amalgam treatment (Odds Ratio = 11.12). Our study showed that mercury from amalgam, activates T-lymphocytes, not only antigen-specifically, but also polyclonally. Amalgam also increases AD prevalence and makes it intractable iatrogenically. Dental amalgam use should be banned to prevent AD. (author abst.)

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