Science Links Japan | Analysis of Binding Structure of Polyamine Ni(III)Complexes with DNA by ESR Spectroscopy.

Analysis of Binding Structure of Polyamine Ni(III)Complexes with DNA by ESR Spectroscopy.

Accession number;01A0228950

Title;Analysis of Binding Structure of Polyamine Ni(III)Complexes with DNA by ESR Spectroscopy.

Author; NAGATOMI YASUAKI (Chuo Univ., Grad. Sch.) NASHIYAMA TAKAMITSU (Chuo Univ., Grad. Sch.) CHIKIRA MAKOTO (Chuo Univ., Grad. Sch.)

Journal Title;Abstracts. Symposium on Biofunctional Chemistry

Journal Code:L0836A

ISSN:

VOL.15th;NO.;PAGE.16-17(2000)

Figure&Table&Reference;FIG.3, REF.2

Pub. Country;Japan

Language;Japanese

Abstract;A new technique to prepare DNA fibers with Ni(III) complexes was developed and the binding structures of some polyamine complexes of Ni(III) were investigated by DNA-fiber ESR spectroscopy. Ni(III)cyclam was found to bind to DNA with two Cl- ions at the axial positions. Ni(III)dioxocyclam on A-form DNA-fiber showed several components; one has no Cl- ion and the other has one Cl- ion at the axial position. Furthermore, one species showed considerable rhombic distortion on the DNA. The bindig structures were found to change with the temperature. (author abst.)

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