Senile Changes in the Brain of a Masked Palm Civet, Paguma larvata.
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Accession number;01A0400197
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| Title;Senile Changes in the Brain of a Masked Palm Civet, Paguma larvata. |
| Author;
KAMIYA S
(Nippon Veterinary And Animal Sci. Univ., Tokyo)
HORI H
(Nogeyama Zoological Gardens Of Yokohama, Yokohama, Jpn)
YAMAMOTO Y
(Nogeyama Zoological Gardens Of Yokohama, Yokohama, Jpn)
TAKEDA H
(Nogeyama Zoological Gardens Of Yokohama, Yokohama, Jpn)
MIYAUCHI E
(Nogeyama Zoological Gardens Of Yokohama, Yokohama, Jpn)
TAKAISHI J
(Nippon Veterinary And Animal Sci. Univ., Tokyo)
YAMAGAMI T
(Nippon Veterinary And Animal Sci. Univ., Tokyo)
YAMANO S
(Nippon Veterinary And Animal Sci. Univ., Tokyo)
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Journal Title;Bulletin of Nippon Veterinary and Animal Science University
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Journal Code:S0144B
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ISSN:0373-8361
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VOL.;NO.49;PAGE.1-4(2000)
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| Figure&Table&Reference;FIG.4, REF.13 |
| Pub. Country;Japan |
| Language;English |
| Abstract;The brain of a 28-year-old male masked palm civet, Paguma larvata, without neurological signs was examined by light microscopy and histochemistry. The amyloid-.BETA.-protein immunostaining revealed that many senile plaques were disseminated throughout the cerebral cortex. A large number of polyglucosan bodies(PGB) were found throughout the brain, especially in the cerebellar cortex. PGB were round, basophilic and PAS-positive structures. They were situated free in the neuropil. Civet PGB were immunoreactive for a monoclonal antibody to human polyglucosan. A list of other changes includes amyloid angiopathy, an accumulation of lipofuscin, axonal spheroids, fibrous thickening of leptomeninges, and perivascular accumulation of lipid-laden cells. However, Alzheimer's neurofibrillary tangles could not be found. (author abst.) |
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