Science Links Japan | Susceptibility of Actinobacillus pleuropneumoniae Strains to Ofloxacin and 19 Commonly Used Antimicrobial Agents.

Susceptibility of Actinobacillus pleuropneumoniae Strains to Ofloxacin and 19 Commonly Used Antimicrobial Agents.

Accession number;01A0400201

Title;Susceptibility of Actinobacillus pleuropneumoniae Strains to Ofloxacin and 19 Commonly Used Antimicrobial Agents.

Author; HIGASHIDE YOSHIHIRO (Nippon Vet. and Anim. Sci. Univ.) TAKAHASHI ISAMU (Nippon Vet. and Anim. Sci. Univ.) YOSHIDA TAKAHARU (Nippon Vet. and Anim. Sci. Univ.) SAKIMURA HIROAKI (Nippon Vet. and Anim. Sci. Univ.) SAITO TAKESHI (Nippon Vet. and Anim. Sci. Univ.) TAKIGAWA YOSHIYASU (Nippon Vet. and Anim. Sci. Univ.) SAWADA TAKUO (Nippon Vet. and Anim. Sci. Univ.)

Journal Title;Bulletin of Nippon Veterinary and Animal Science University

Journal Code:S0144B

ISSN:0373-8361

VOL.;NO.49;PAGE.27-32(2000)

Figure&Table&Reference;TBL.2, REF.27

Pub. Country;Japan

Language;Japanese

Abstract;Susceptibility of Actinobacillus pleuropneumoniae strains to ofloxacin(OFLX) and 19 commonly used antimicrobial agents was compared by median minimum inhibitory concentrations (MIC50S). As the results, the bacterial strains showed highest susceptiblity to OFLX with 0.05.MU.g/ml. The strains were also highly susceptible to norfloxacin, trimethoprim(TMP) and oxolinic acid with 0.1-0.2.MU.g/ml, followed by a combination product of sulfamethoxazole(SMX) 5:TMP 1 (ST 5:1) with 0.39.MU.g/ml, and tetracycline, doxycycline, ampicillin, chloramphenicol, thiamphenicol and SMX 20:TMP 1 (ST 20:1) with 0.78.MU.g/ml, respectively. The strains were moderately susceptible to oxytetracycline, pipemidic acid, nalidixic acid, chlortetracycline and tiamulin with 1.56-3.13.MU.g/ml. On the other hand, low susceptibility of the bacteria was shown to kanamycin, streptomycin, tylosin and SMX with 12.5-50.MU.g/ml. The MIC50 of SMX was 1,024 fold higher than that of OFLX. (author abst.)

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