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Accession number;01A0533956
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| Title;Effects of Endothelin-1 on Choroidal Vessels. 2. Study Using Indocyanine Green Videoangiography. |
| Author;
NAKAGAWA HIDEKI
(Okayamadai I Gankagakukyoshitsu)
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Journal Title;Journal of Japanese Ophthalmological Society
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Journal Code:Z0666A
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ISSN:0029-0203
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VOL.105;NO.5;PAGE.301-307(2001)
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| Figure&Table&Reference;FIG.7, REF.17 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Purpose: The effects of intravenous administration of endothelin-1 (ET-1) on choroidal arteries were studied using indocyanine green videoangiography. Methods: The changes in caliber of the choroidal arteries in eight albino rabbits were examined using indocyanine green videoangiography with a scanning laser ophthalmoscope and an image analysis system. Results: Administration of 10-9mol/kg of ET-1 induced a significant reduction in diameter of 50.5-80.1% (median=64.15%) 5 minutes after administration. The constriction continued for more than 60 minutes. Conclusion: This study demonstrates that intravenous administration of ET-1 induces long-lasting constriction of choroidal arteries. This suggests that ET-1 may participate in the regulation of choroidal artery tone. (author abst.) |
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