Rationalization and Standardization of Pharmaceutical Services. (I). Development and Evaluation of a Computer System for Checking Compatibility of Injections.

Accession number;01A0773148
Title;Rationalization and Standardization of Pharmaceutical Services. (I). Development and Evaluation of a Computer System for Checking Compatibility of Injections.
Author; YOSHIOKA MUTSUNOBU (Takarazukashibyoin Yakuzaibu) TSUJI TAKASHI (Takarazukashibyoin Yakuzaibu) MASAKI KOICHI (Takarazukashibyoin Yakuzaibu) MORIOKA MIHO (Takarazukashibyoin Yakuzaibu) WATARI MASAKATSU (Takarazukashibyoin Yakuzaibu) ONISHI NORIAKI (Kyotoyakudai Byoin Yakugakukyoshitsu) YOKOYAMA TERUYOSHI (Kyotoyakudai Byoin Yakugakukyoshitsu) KURODA KAZUO (Takarazukashibyoin Yakuzaibu)
Journal Title;Japanese Journal of Pharmaceutical Health Care and Sciences
Journal Code:Y0888A
ISSN:1346-342X
VOL.27;NO.4;PAGE.323-330(2001)
Figure&Table&Reference;FIG.7, TBL.3, REF.9
Pub. Country;Japan
Language;Japanese
Abstract;Recently hospital pharmacists have been devoting more energy to inpatients rather than outpatients, and regarding injections it is increasingly more important to predict and avoid interactions between or among them simply to assort them. In this study, to secure the stability and safety of injections prescribed for inpatients by doctors, we developed a clinically useful computer system to check some incompatibilities between medicines. The database used in the computer system for chemical interactions comprised of information on combinations between two drugs obtained from formal textbooks or the literature, while that for physical interactions included the results of the pH change examination for each medicine. When comparing the two periods during 6 months before and after introducing this system, the incidence of turbidity due to interactions and economical loss after introduction were substantially smaller than those before introduction, thus suggesting that this system could qualitatively and economically improve the service for injections performed by hospital pharmacists. In addition, suggestions made by doctors and nurses using this system have resulted in clinically favorable findings, and consequently this system is highly evaluated at our hospital. Furthermore, at one month after introducing this system, it was shown to be very useful for particularly avoiding interactions in the same syringe when mixing two medicines or more. (author abst.)