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Accession number;01A0530499
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| Title;Analysis of Carotid Artery Arterioscleosis and Activation of Peripheral Blood Monocyte CD 36 Antigen in Type 2 Diabetic Patients. |
| Author;
SEINO HIROAKI
(Otasogobyoin Otanishinochibyoin Tonyobyose Naika)
WATANABE HIROYA
(Otasogobyoin Otanishinochibyoin Tonyobyose Naika)
MUTO GEN
(Otasogobyoin Otanishinochibyoin Tonyobyose Naika)
KITAGAWA MASAYUKI
(Otasogobyoin Otanishinochibyoin Tonyobyose Naika)
YAMAZAKI TOSHIRO
(Otasogobyoin Otanishinochibyoin Tonyobyose Naika)
ATSUMI MAKIKO
(Otasogobyoin Otanishinochibyoin Tonyobyose Naika)
KIKUCHI HIROAKI
(Otasogobyoin Otanishinochibyoin Tonyobyose Naika)
ABE RYUZO
(Otasogobyoin Otanishinochibyoin Tonyobyose Naika)
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Journal Title;Journal of the Japan Diabetic Society
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Journal Code:Z0279B
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ISSN:0021-437X
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VOL.44;NO.4;PAGE.309-314(2001)
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| Figure&Table&Reference;FIG.1, TBL.4, REF.18 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;To clarify the relationship between arteriosclerosis of carotid artery and DC 36 antigen activation in peripheral blood monocytes in type 2 diabetes, we analyzed the activation of CD 36 by histogram using flow cytometry for 106 cases of type 2 diabetes divided into 3 groups: Group I, low activation; Group II, intermediate activation; and Group III, high activation. A comparison of intimamediathickness (IMT) in carotid arteries for the 3 groups should no significant difference between them. The frequency of atheromatous plaque formation for Group I was 43%, for Group II 63%, and for Group III 92%, indicating that the frequency of plaque formation significantly higher (p<0.05) with increasingly activate CD 36 in peripheral blood monocytes. CD 36 activation of peripheral blood monocytes thus appears to be correlated with plaque formation in carotid arteries in type 2 diabetic patients. (author abst.) |
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