Further Development of Pharmacy Services of Hospital Pharmacists. Self-Monitoring of Side Effects in Outpatients with Breast Cancer.

Accession number;01A0607667
Title;Further Development of Pharmacy Services of Hospital Pharmacists. Self-Monitoring of Side Effects in Outpatients with Breast Cancer.
Author; KITADA NORIAKI (Takarazukashibyoin Yakuzaibu) SEKIDO SATOKO (Takarazukashibyoin Yakuzaibu) KOBAYASHI MUTSUMI (Takarazukashibyoin Yakuzaibu) WATARI MASAKATSU (Takarazukashibyoin Yakuzaibu) ORIYAMA TAKESHI (Takarazukashibyoin Geka) KURODA KAZUO (Takarazukashibyoin Yakuzaibu)
Journal Title;Japanese Journal of Pharmaceutical Health Care and Sciences
Journal Code:Y0888A
ISSN:1346-342X
VOL.27;NO.3;PAGE.275-281(2001)
Figure&Table&Reference;FIG.6, TBL.1, REF.15
Pub. Country;Japan
Language;Japanese
Abstract;In the present study, we implemented the self-monitoring of side effects in surgical outpatients with breast cancer to improve their quality of life (QOL). Self-monitoring of side effects was carried out by entering the early symptoms (myelosuppression and gastrointestinal failures) on a specially prepared side effect checking-sheet. Six outpatients participated in this study. The chemotherapeutic regimens consisted of cyclophosphamide, adriamycin and 5-fluorouracil, i.e. CAF therapy. In these patients, a mild myelosuppression was seen after the completion of half of each protocol (from approximately day 8 to 14). However, there was no relationship between the early symptoms of myelosuppression ("fever", "general fatigue" and "throat pain" score) and the number of leucocytes. On the other hand, the self-monitoring of side effects showed a better influence on the subjective score for the symptoms of gastrointestinal failures (i.e. "nausea"). In the present study, the self-monitoring of side effects in outpatients with breast cancer was thus suggested to be a useful tool for improving the patient's QOL. (author abst.)