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Accession number;01A0680949
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| Title;Characteristics of Coronary Artery Atherosclerosis in Diabetic Patients: Assessments by Intra-vascular Ultrasound. |
| Author;
OHASHI SATOSHI
(Juntendodai Junkankinaika)
MIYAUCHI KATSUMI
(Juntendodai Junkankinaika)
KURATA TAKESHI
(Juntendodai Junkankinaika)
SATO HITOSHI
(Juntendodai Junkankinaika)
SAKURAI HIDEHIKO
(Juntendodai Junkankinaika)
DAIDA HIROYUKI
(Juntendodai Junkankinaika)
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Journal Title;Journal of the Japan Diabetic Society
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Journal Code:Z0279B
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ISSN:0021-437X
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VOL.44;NO.6;PAGE.481-488(2001)
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| Figure&Table&Reference;FIG.1, TBL.5, REF.31 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;To clarify the characteristics of diabetic coronary atherosclerosis, we analyzed coronary angiograms and intra-vascular ultrasound imaging of coronary arteries in 40 diabetic and 80 non-diabetic patients. Cross-sectional vessel area and lumen area were measured by planimetry in 716 segments of the right or left coronary arteries. Target segments of percutaneus transluminal coronary angioplasties were excluded. Plaque area (area within the cross-sectional vessel area minus the lumen area) and percent plaque area (percentage of plaque area divided by the cross-sectional vessel area) were calculated. The analysis of the coronary angiograms demonstrated that the diabetic patients had a significantly higher prevalence of multivessel disease (65% vs. 42%, p=0.0177) and higher levels of coronary score by the segmental distribution method than non-diabetic patients (26 points vs. 20 points, p=0.0488). However, the mean percent of stenosis and the morphology of the lesions in the coronary angiograms were not significantly different. Intra-vascular ultrasound imaging analysis demonstrated that the coronary arteries of diabetic patients had significantly smaller lumen areas in the left anterior descending arteries and in the right coronary arteries than those of non-diabetic patients. Diabetic patients also had a significantly larger percent plaque area in the right coronary antery than non-diabetic patients. These results suggest that diabetic patients, have more diffuse and longer lesions than non-diabetic patients, even in angiographically normal segments. (author abst.) |
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