Analysis of Interstitial Pneumonia in Patients with Rheumatoid Arthritis Using High-Resolution Computed Tomography (HRCT).

Accession number;01A0695925
Title;Analysis of Interstitial Pneumonia in Patients with Rheumatoid Arthritis Using High-Resolution Computed Tomography (HRCT).
Author; FUKUYA HIDENARI (Tokyoshidai Ichikawasogobyoin Naika)
Journal Title;Journal of the Medical Society of Toho University
Journal Code:G0654A
ISSN:0040-8670
VOL.48;NO.3;PAGE.257-263(2001)
Figure&Table&Reference;FIG.3, TBL.6, REF.24
Pub. Country;Japan
Language;Japanese
Abstract;Interstitial pneumonia (IP) is one of the most important visceral complications in rheumatoid arthritis (RA), and can result in increased morbidity and mortality among RA patients. However, the prevalence and clinical profile of IP in RA is not well understood. In the present study, we analyzed the chest X-ray CT films of 64 RA patients and compared these CT images with clinical manifestations. Abnormal interstitial shadows were detected in 64.1% of RA patients on HR-CT tests, compared with 46.3% on plain chest X-rays. Among patients with interstitial shadows on plain X-ray films, 25% had no such findings on CT films. The most prominent type of interstitial change was a hazy shadow, seen in 95.1% of RA patients with IP. Nodular shadows and ring-shaped opacities were seen in 70.0 and 65.8% of patients, respectively. Several factors correlated with the presence of IP, including advanced age, male sex, a history of smoking, the presence of subcutaneous nodules, a positive test for anti-nuclear antibodies, and elevated serum IgA levels. There was no correlation between the presence of IP and the duration of illness, the degree of bone destruction, or type of medication. (author abst.)