Incidence of GAD Autoantibodies in the Diabetic Patients Visited a Diabetic Clinic.

Accession number;01A0793357
Title;Incidence of GAD Autoantibodies in the Diabetic Patients Visited a Diabetic Clinic.
Author; KAWAI KOICHI (Kawaikurinikku) MOTOHASHI SHINOBU (Kawaikurinikku) SUGAWARA KAORU (Kawaikurinikku) URAYAMA OSAMU (Kawaikurinikku)
Journal Title;Journal of the Japan Diabetic Society
Journal Code:Z0279B
ISSN:0021-437X
VOL.44;NO.7;PAGE.577-579(2001)
Figure&Table&Reference;TBL.1, REF.7
Pub. Country;Japan
Language;Japanese
Abstract;Clinical infomations on 1,408 patients - 46 with insulin-dependent diabetes mellitus (IDDM) and 1362 with non-insulin-dependent diabetes mellitus (NIDDM) - who visited a diabetes mellitus clinic were registered into a using software "CoDiC", a modification of "NovoNet" for outcome reseach. Titers of autoantibodies against glutamic acid decarboxylase (GAD) were measured in all IDDM and 74.3% of NIDDM patients. Those found positive to GAD antibody numbered 45.7% of IDDM and 1.8% of NIDDM patients. Based on this data and a clinical course of GAD antibody positive patients with impaired glucose tolerance, we discuss the clinical significance of measuring GAD antibodies. (author abst.)