Effect of physical training on insulin resistance and alpha-glucosidase activity in early stage symptom of type 2 diabetic mice.
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Accession number;01A0626983
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| Title;Effect of physical training on insulin resistance and alpha-glucosidase activity in early stage symptom of type 2 diabetic mice. |
| Author;
MIURA T
(Suzuka Univ. Medical Sci., Mie, Jpn)
NISHIDA T
(Suzuka Univ. Medical Sci., Mie, Jpn)
ISIHARA E
(Suzuka Univ. Medical Sci., Mie, Jpn)
ISHIDA T
(Suzuka Univ. Medical Sci., Mie, Jpn)
TANIGAWA K
(Suzuka Univ. Medical Sci., Mie, Jpn)
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Journal Title;Biomed Res
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Journal Code:Z0236B
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ISSN:0388-6107
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VOL.22;NO.1;PAGE.59-61(2001)
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| Figure&Table&Reference;FIG.3, REF.15 |
| Pub. Country;Japan |
| Language;English |
| Abstract;Restricted diet and physical training (PT) are the first treatments for early stage symptom of type 2 diabetes. We studied the effect of PT on insulin resistance in pheripheral tissues and alpha-glucosidases in small intestine of KK-Ay mice, an animal model of type 2 diabetes. The blood glucose and plasma insulin level in KK-Ay mice were significantly decreased after 3 weeks of PT when compared with control group (no-exercise). PT caused decrease in insulin resistance, which may be beneficial, for insulin tolerance. However, PT had little, if any, effect on alpha-glucosidase activity in small intestine of KK-Ay mice. (author abst.) |
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