Physiological Changes in Skin During Pregnancy and Sex Hormone.
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Accession number;01A1010592
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| Title;Physiological Changes in Skin During Pregnancy and Sex Hormone. |
| Author;
FUSE YOJI
(Teikyodai I Mizonokuchibyoin Sanfujinka)
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Journal Title;Journal of the Medical Society of Toho University
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Journal Code:G0654A
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ISSN:0040-8670
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VOL.48;NO.4/5;PAGE.347-352(2001)
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| Figure&Table&Reference;FIG.5, TBL.2, REF.13 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;A physiological study of basic skin changes during pregnancy was performed on 25 normal pregnant women. Both skin water content and skin water-holding capacity increased during the course of pregnancy, and these changes were due to the water storage promoting function of estrogen. The sebum content greatly increased in the 1st trimester, after which it gradually decreased. These changes were most likely caused by hCG and/or estrogen. The wax esters/cholesterol +cholesterol esters ratio showed evidence of sebaceous gland activity, decreased with the course of pregnancy, and increased in puerperium. Both triglyceride and wax esters dramatically increased in the 1st trimester, decreasing gradually with the course of pregnancy, along with estrogen. However, it is important to note that the ratio of squalene increased during the course of pregnancy, conceivably due to dehydroepeandrosterone (DHA) action. The results suggest that physiological changes in the skin during pregnancy were mainly affected by estrogen. (author abst.) |
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