Occult retinal pigment epithelial detachment in a case of hyperviscosity syndrome.

Accession number;00A0403340
Title;Occult retinal pigment epithelial detachment in a case of hyperviscosity syndrome.
Author; OGATA NAOKO (Kansai Med. Univ.) TAKAHASHI KANJI (Kansai Med. Univ.) IDA HISASHI (Kansai Med. Univ.) FUKUCHI TOSHIO (Kansai Med. Univ.) KONDO MIKA (Kansai Med. Univ.)
Journal Title;Japanese Journal of Clinical Ophthalmology
Journal Code:Z0515B
ISSN:0370-5579
VOL.54;NO.3;PAGE.335-338(2000)
Figure&Table&Reference;FIG.3, REF.16
Pub. Country;Japan
Language;Japanese
Abstract;A 62-year-old male presented with bilateral metamorphopsia and visual impairment of 6 months' duration. His corrected visual acuity was 0.5 right and 0.3 left. Funduscopy showed exudative retinal visual detachment of about 5 disc diameters in the posterior fundus bilaterally. Both eyes showed engorged retinal veins, retinal hemorrhage and microaneurysms. Detachment of retinal pigment epithelium(RPE) was detected outer to the area of retinal detachment by optical coherence tomography. Laboratory studies showed hyperglobulinemia, leading to the diagnosis of hyperviscosity syndrome due either to primary macroglobulinemia or multiple myeloma. Fluorescein angiography consistently failed to show findings of RPE detachment. This feature appeared to be due to accummulation of viscous abnormal immunoglobulin protein in the sub-RPE space. (author abst.)