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Accession number;02A0151480
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| Title;A Case of Squamous Cell Carcinoma Arising from Mature Cystic Teratoma Which Developed Hypercalcemia with PTHrP Production. |
| Author;
SATO KEN'ICHIRO
(Shin'nnittetsu Muroran Sogo Byoin)
MIZUUCHI HIDEMITSU
(Mizuchisankafujinka(hokkaido))
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Journal Title;Acta Obstetrica et Gynaecologica Japonica
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Journal Code:F0923A
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ISSN:0300-9165
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VOL.54;NO.1;PAGE.42-46(2002)
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| Figure&Table&Reference;FIG.4, REF.31 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;We treated a case of squamous cell carcinoma arising from mature cystic teratoma in a 73-year-old patient who developed hypercalcemia with production of parathyroid hormone-related protein. The tumor size was 13*8cm, and the serum calcium level was 11.7mg/dl. Despite poor preoperative general condition, dramatic improvement was observed postoperatively and serum calcium decreased to the normal range immediately. The serum level of PTHrP was 250.2pmol/l and intact PTH was 10pg/ml preoperatively. ABC immunohistochemical staining detected expression of PTHrP in the cancer cell cytoplasm. We therefore diagnosed this case as hypercaicemia with PTHrP production from the ovarian carcinoma. (author abst.) |
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