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Accession number;02A0304363
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| Title;Regulation of Gene Expression using Plasmid-Carbohydrate Conjugate and Lectine. |
| Author;
MATSUURA KAZUNORI
(Kyushu Univ., Grad. Sch.)
HAYASHI KATSUHIRO
(Nagoya Univ., Grad. Sch.)
KOBAYASHI KAZUKIYO
(Nagoya Univ., Grad. Sch.)
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Journal Title;Abstracts. Symposium on Biofunctional Chemistry
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Journal Code:L0836A
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ISSN:
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VOL.16th;NO.;PAGE.14-15(2001)
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| Figure&Table&Reference; |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;This paper proposes an artificial system to regulate gene expression, which has been inspired by chromatin remodeling in biological system. The complex between plasmid DNA-lactose conjugate and .BETA.-galactose-specific RCA120 lectin was constructed as a mimic of chromatin made of DNA and histone. of the plasmid-lactose conjugate was repressed by RCA120 and the recovered by adding lactose or lactose-carrying polymer to the repression system, whereas such repression by RCA120 was not observed in native plasmid DNA. (author abst.) |
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