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Accession number;02A0146457
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| Title;A Clinicopathological Study of 17 Cases of Cholesterol Crystal Embolization. |
| Author;
ONISHI YASUHIKO
(Tohodai I Hifukagakudaiichi)
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Journal Title;Journal of the Medical Society of Toho University
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Journal Code:G0654A
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ISSN:0040-8670
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VOL.48;NO.6;PAGE.435-443(2001)
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| Figure&Table&Reference;FIG.8, TBL.4, REF.18 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;The findings from a retrospective clinicopathological study of 17 cases of cholesterol crystal embolization syndrome (CCE) are presented and discussed. The age of the patients ranged from 53 to 82 years, with a mean of 70.8 years. The male/female ratio was 3.3:1(13:4). 64.7% (11/17) of the 17 cases had a history of diabetes, and 13 (76.5%) had developed CCE after angiocatheterization by percutaneous transluminal coronary angioplasty (PTCA), coronary angiography (CAG) or percutaneous transluminal angioplasty (PTA). Two patients died of CCE, the rest are either alive or have died due to another disease. Cutaneous manifestations were noted in all cases, and were the most frequent clinical evidence of CCE in this study. Livedo reticularis (94.1% of the 17 cases) and cyanosis (purple or blue toes: 58.8% of the 17 cases) were noted, mainly on the patients' toes and soles. This underlines the importance of careful observation and skin biopsy for early diagnosis. Dermatopathological examination of the histological features of the embolized arteries revealed that the 17 cases could be divided into three groups on the basis of the period of time following cholesterol crystals embolization: early phase (embolized phase), intermediate phase (granulomatous phase) and late phase (occluded phase). (author abst.) |
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