Effect of Bone Formation on Calcium Hydroxide Paste.

Accession number;02A0185118
Title;Effect of Bone Formation on Calcium Hydroxide Paste.
Author; ITO TAICHI (Tokyoshidai Shikahozongakudaini) SHIBUKAWA YOSHIHIRO (Tokyoshidai Shikahozongakudaini) KAWAI HIDETAKA (Tokyoshidai Shikahozongakudaini) AMANO YASUHIKO (Tokyoshidai Shikahozongakudaini) YAMADA SATORU (Tokyoshidai Shikahozongakudaini)
Journal Title;Nippon Koku Inpuranto Gakkaishi
Journal Code:G0262C
ISSN:0914-6695
VOL.14;NO.4;PAGE.557-560,561-562(2001)
Figure&Table&Reference;FIG.8, TBL.1, REF.16
Pub. Country;Japan
Language;Japanese
Abstract;The purpose of this study was to evaluate how the application of OSTEOINDUCTAL after tooth extraction affects alveolar bone formation. OSTEOINDUCTAL is a calcium hydroxide pharmaceutical. Twenty-one Wistar rats were divided into two groups. In both groups, teeth were extracted. The control group underwent no further treatment. OSTEOINDUCTAL was applied after tooth extraction in the experimental group. The experimental animals were sacrificed for specimen preparation at 4 weeks and 8 weeks. After paraffin embedding, tissues were sliced at 5.MU.m thickness and stained with H-E. From each specimen, the proportions of the bone dimensions were calculated using a Micro Scope System (MS-803, MORITEX, Tokyo, Japan). In the control group, the bone formation was slight at 4 postoperative weeks, and a pit formed by the invasion of the gingival connective tissue after extraction of the tooth lacuna was clearly present. In the experimental group, considerable new bone was formed. The experimental group had significantly more the bone formation at 4 weeks. However, at 8 weeks, the difference between the control and the experimental groups was only slight. The results of this study suggest that OSTEOINDUCTAL may speed up postoperative bone induction. (author abst.)