Clinical and Laboratory Features of Extraglandular Involvements in Sjoegren's Syndrome: Gastro-intestinal, Hepato-pancreatic, Thyroidal and Nervous System Manifestations.
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Accession number;02A0208855
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| Title;Clinical and Laboratory Features of Extraglandular Involvements in Sjoegren's Syndrome: Gastro-intestinal, Hepato-pancreatic, Thyroidal and Nervous System Manifestations. |
| Author;
YOSHIDA TADASHI
(Hoshiyakudai Yaku Byotaiseirigaku)
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Journal Title;Prog Med
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Journal Code:F0664B
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ISSN:0287-3648
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VOL.22;NO.1;PAGE.34-37(2002)
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| Figure&Table&Reference;TBL.2, REF.10 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Sjoegren's syndrome (SjS) is an autoimmune disease that mainly affects exocrine glands and usually presents as a persistent dryness due to functional impairment of the salivary and lacrimal glands. The histologic hallmark is a focal lymphocytic infiltration of the exocrine gland, and the spectrum of the disease extends from an organ-specific autoimmune disease (autoimmune exocrinopathy) to a systemic process (central nervous system involvement). Considering the developmental, functional and pathologic similarities of the hepato-pancreatic, thyroidal and salivary gland, the association of these diseases and SjS may have not only clinical but also etiopathogenic significance. (author abst.) |
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