Science Links Japan | Clinical Value of Periventricular Low-intensity Areas Detected by Fluid Attenuated Inversion Recovery (FLAIR): Relationships between Perinatal Vital Parameter and Neonatal MRI.

Clinical Value of Periventricular Low-intensity Areas Detected by Fluid Attenuated Inversion Recovery (FLAIR): Relationships between Perinatal Vital Parameter and Neonatal MRI.

Accession number;02A0168946

Title;Clinical Value of Periventricular Low-intensity Areas Detected by Fluid Attenuated Inversion Recovery (FLAIR): Relationships between Perinatal Vital Parameter and Neonatal MRI.

Author; KADOWAKI SACHIKO (Naganokenkodomobyoin Shinseijika) IWATA OSUKE (Naganokenkodomobyoin Shinseijika) TAMURA MASANORI (Naganokenkodomobyoin Shinseijika) HIROMA TAKEHIKO (Naganokenkodomobyoin Shinseijika) UETA IKUYA (Naganokenkodomobyoin Shinseijika) NAKAMURA TOMOHIKO (Naganokenkodomobyoin Shinseijika) HIRABAYASHI SHIN'ICHI (Naganokenkodomobyoin Shinkeika) FUEKI NOBORU (Naganokenkodomobyoin Shinkeika) KONDO YOSHIAKI (Naganokenkodomobyoin Hoshasenka)

Journal Title;Journal of the Japan Pediatric Society

Journal Code:F0896A

ISSN:0001-6543

VOL.106;NO.1;PAGE.29-37(2002)

Figure&Table&Reference;FIG.6, TBL.4, REF.11

Pub. Country;Japan

Language;Japanese

Abstract;A follow-up study was performed to assess the correlation among the incidence of periventiricular low intensities (PVLI) on MRI (magnetic resonance imaging) FLAIR (fluid attenuated inversion recovery) imaging, clinical evidence of perinatal insults that may cause white matter damage, and the outcome of the infants. We evaluated periventricular white matter lesions of 329 neonates whose MRI were obtained befor two months corrected age. The detective rate of periventricular abnormalities on FLAIR imaging was significantly higher than that of T1-T2 weighted imaging. The most typical lesion detected on FLAIR imaging was periventricular low intensities (PVLI), frequently observed in the neonates with a history of preterm labour, very low birth weight, birth asphyxia and severe respiratory failure. Although we could not characterize the risk factors of PVLI, the incidence of PVLI had a strong correlation with the scores of motor and developmental tests at 12 and 36-months corrected age. In conclusion, FLAIR imaging, detecting the border zone damage of white matter, would be a strong tool to pick out neonates at high risk of neurological disturbances from those without clinical evidence of neurological insults in the neonatal period. (author abst.)

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