|
Accession number;02A0305812
|
| Title;The Mast Cell Stabilizers: The Mechanisms of Action and the Usefulness. |
| Author;
OKAMOTO YOSHITAKA
(Yamanashiidai Jibiinkoka)
|
Journal Title;Prog Med
|
Journal Code:F0664B
|
ISSN:0287-3648
|
|
VOL.22;NO.2;PAGE.358-361(2002)
|
| Figure&Table&Reference;FIG.2, REF.18 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Disodium cromoglycate, tranilast, pemirolast and AA673 are called as the mast cell stabilizers and are potent, long-acting effective anti-nasal allergic agents. Their mechanisms of action is thought to be inhibition of the release of chemical mediators, such as histamine and leukotriens, from tissue mast cells. They are slow-acting drugs and the improvement of nasal obstruction is thought to be superior to that of anti-histamines. However, their precise mechanisms of the action in human in vivo are not well clarified yet. We reviewed the role of these mast cell stabilizers in the treatment of allergic rhinitis. (author abst.) |
|
|
|
Related Articles;
|
