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Accession number;02A0351395
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| Title;Bacterial Strains Isolated from Upper Pharynx of Young Children Suffering from Acute Respiratory Tract Infections. |
| Author;
ENDO HIROKO
(Labor Welf. Crop., Tohoku Rosai Hospital)
KAYAMA YASUKO
(Kayamashonikaiin)
KAWAMURA KAZUHISA
(Kawamurakodomokurinikku)
SATO NORIKO
(Norikoshonika)
SHIMODA HARUMI
(Katsuranaikakodomokurinikku)
TAKAMATSU NORIMITSU
(Takamatsushonikaiin)
TANO MIYO
(Kimachishonikaiin)
WATAYA KAORU
(Ikeda Kurinikku)
UBUKATA KIMIKO
(Inst. of Microb. Chem.)
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Journal Title;Journal of the Japan Pediatric Society
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Journal Code:F0896A
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ISSN:0001-6543
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VOL.106;NO.4;PAGE.472-481(2002)
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| Figure&Table&Reference;FIG.6, TBL.1, REF.17 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Acute respiratory tract infection often becomes intractable in children under 3 years of age. We, thus, conducted bacteriological examination of the scrubbed specimen from upper pharynx in 187 children suffered from acute respiratory tract infection. One hundred and thirty-one children (group I) received no previous treatment while remaining 56 (group II) had not recovered in spite of antibiotics treatment at least for 3 days. S. pneumoniae was detected in 76 of group I (58.8%) and 30 of group II (53.6%), respectively. The frequency of PCG-resistant S. pneumoniae was higher in group II than in group I (96.7 vs. 77.6%, p<0.05). Group II also showed higher frequency of macrolide-resistant S. pneumoniae (89.7 vs. 71.4%, p<0.05) and much lower frequency of S. pneumoniae sensitive to both kinds of drugs (0 vs. 15.7%, p<0.01). H. influenzae was detected in 50 of group I (38.2%) and 21 of group II (37.5%), respectively. The frequency of BLNAR was 40.4% in group I. The resistant bacteria were detected more frequently in cases associated with pneumonia and/or otitis media than in non-complicated cases. Furthermore children cared in day nursery showed higher prevalence of the resistant bacteria compared with those cared at home. We conclude that resistant bacteria play an important role in the pathogenesis of intractable and/or complicated acute respiratory tract infections in children under 3 years of age. Group day nursery may increase the risk of the prevalence of resistant bacteria. (author abst.) |
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