Monthly Cycles of 1-week Therapy with Itraconazole for Patients with Tinea Pedis.

Accession number;02A0462195
Title;Monthly Cycles of 1-week Therapy with Itraconazole for Patients with Tinea Pedis.
Author; KOBAYASHI HIROMI (Osakashidai Daigakuin'igakukenkyuka Hifubyotaigaku) MIZUNO NOBUYUKI (Osakashidai Daigakuin'igakukenkyuka Hifubyotaigaku) NAKANISHI TAKESHI (Osakashidai Daigakuin'igakukenkyuka Hifubyotaigaku) FUKAI KAZUYOSHI (Osakashidai Daigakuin'igakukenkyuka Hifubyotaigaku) ISHII MASAMITSU (Osakashidai Daigakuin'igakukenkyuka Hifubyotaigaku) MORIMOTO KENSUKE (Nihon'idai Chibahokusobyoin Hifuka)
Journal Title;Japanese Journal of Medical Mycology
Journal Code:G0589A
ISSN:0916-4804
VOL.43;NO.2;PAGE.73-77(2002)
Figure&Table&Reference;FIG.8, REF.14
Pub. Country;Japan
Language;Japanese
Abstract;Monthly cycles of 1-week therapy with oral itraconazole at 200 mg daily for tinea pedis was assessed to determine its acceptability to patients. Thirty-four patients (17 men and 17 women) with intractable tinea pedis, with informed consent, took 200 mg of itraconazole once daily for one week over a month period until mycological studies showed negative results for up to 4 months. The overall mycological effectiveness was about 80% after this therapy. Information was also gathered on the influence of this therapy on the patient's quality of life by questionnaires. Nineteen (70%) among the 27 patients who answered the questionnaire preferred this 1-week administration of itraconazole over a month-long period compared with continuous daily therapy. Twenty-two (81%) preferred this therapy over topical treatment. We recommend to this therapy be added for the treatment of intractable tinea pedis. (author abst.)
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