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Accession number;02A0472897
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| Title;Effect of methylphenidate on brain function in children with attention deficit hyperactivity disorder. |
| Author;
YAMADA JUNJI
(Fukuiidai Seishin'igaku)
MURATA TETSUTO
(Fukuiidai Seishin'igaku)
OMORI MASAO
(Fukuiidai Seishin'igaku)
KOBAYASHI TOSHIO
(Fukuikenbyoin Seishinshinkeise)
WADA YUJI
(Fukuiidai Seishin'igaku)
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Journal Title;Annual Report of the Pharmacopsychiatry Research Foundation
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Journal Code:Y0939A
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ISSN:0286-7591
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VOL.;NO.34;PAGE.213-220(2002)
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| Figure&Table&Reference;FIG.7, REF.26 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Deficits of executive functions have been reported in children with attention deficit hyperactivity disorder(ADHD). The purpose of the present study was to investigate the effects of stimulant medication(methylphenidate, MPH) on neuropsychological tests and electroencephalogram(EEG) of these patients. Three tests of executive function(Continuous Performance Test, Stroop Color-Word Test, Trail Making Test) and EEG were performed in 7 outpatients who met the DSM-IV criteria for ADHD (mean, 11 years) before and after MPH administration. The aspects of working memory, planning ability, and sustained attention included in these neuropsychological tests were improved after the MPH administration. EEG records without drowsiness, muscle activity, or other artifacts could be analyzed for only 3 patients. EEGs tended to show a decrease in absolute power of theta and slow alpha band and an increase in beta band power after MPH administration compared with pre-drug condition. The present study provides further evidence that MPH improves executive function in ADHD. (author abst.) |
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