Effect of Keishi-bukuryo-gan on asymptomatic cerebral infarction for short term.

Accession number;02A0476296
Title;Effect of Keishi-bukuryo-gan on asymptomatic cerebral infarction for short term.
Author; GOTO H (Toyama Medical And Pharmaceutical Univ., Toyama, Jpn) SHIMAKA Y (Toyama Medical And Pharmaceutical Univ., Toyama, Jpn) MITSUMA T (Iizuka Hospital, Fukuoka, Jpn) SHINTANI T (Kanebo Memorial Hospital, Hyogo, Jpn) NAGASAKA K (Suwa Central Hospital, Nagano, Jpn) GOTO S (Miyanomori Memorial Hospital, Hokkaido, Jpn) SHIBAHARA N (Toyama Medical And Pharmaceutical Univ., Toyama, Jpn) TERASAWA K (Toyama Medical And Pharmaceutical Univ., Toyama, Jpn)
Journal Title;Journal of Traditional Medicines
Journal Code:Y0941A
ISSN:1340-6302
VOL.19;NO.2;PAGE.46-50(2002)
Figure&Table&Reference;FIG.1, TBL.3, REF.17
Pub. Country;Japan
Language;English
Abstract;The efficacy of Keishi-bukuryo-gan in patients suffering from asymptomatic cerebral infarction was studied. 142 patients, 32 males and 110 females, with a mean age of 68.9 years, were enrolled and analyzed, and 139 completed the study. They were given Keishi-bukuryo-gan extract(7.5g/day) three times a day for 12 weeks. In comparison to the beginning of the study, Keishi-bukuryo-gan showed improvement with statistical significance in the mean revised version of Hasegawa's dementia scale, Apathy scale and Self-rating depression scale. The number of patients with subjective symptoms as headdullness, headache and dizziness decreased by the treatment with Keishi-bukuryo-gan, and diastolic blood pressure was decreased with statistical significance as compared to the beginning of the study. These results suggest that Keishi-bukuryo-gan is effective against dysfunction of acknowledgment, emotional disorder and subjective symptoms with asymptomatic cerebral infarction. (author abst.)