Antibiotic-associated Colitis in Senile Patiens.

Accession number;02A0520368
Title;Antibiotic-associated Colitis in Senile Patiens.
Author; YAMAKADO SUSUMU (Tokyototamarojin'iryose Shokakika)
Journal Title;Japanese Journal of Geriatrics
Journal Code:Z0680A
ISSN:0300-9173
VOL.39;NO.3;PAGE.271-273(2002)
Figure&Table&Reference;FIG.1, TBL.2, REF.15
Pub. Country;Japan
Language;Japanese
Abstract;Antibiotic-associated colitis (AAC) is a relatively frequent disorder in the senile population. Because of the change of life style in the elderly, the clinical pattern of AAC may be varied. The causative antibiotics, duration of adminisration, duration from taking antibiotics to onset of symptoms, background disorders, symptoms. laboratory data, therapies and prognosis in patients with AAC were investigated retrospectively in 54 cases of averaging 80.5 year old in this hospital. The patients with pseudomembranous colitis (PMC) are older and with a greater preponderance of female gender than patients with acute hemorrhagic colitis. Antimicrobial agents that frequently induced AAC are cephalosporins and penicillins. Symptoms in patients with PMC are diarrhea, abdominal cramping pain and fever. The most common background diseases were neurological and psychiatric disorders. Furthermore, recent advances in understanding the mechanism of toxin A-mediated colinic inflammation, and the management of AAC are reported. (author abst.)
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