Science Links Japan | Recent advance in endocrine pathology in 2002. Hypophysis. A case of growth hormone producing hypophyseal adenoma manifested by exhibiting diabetes insipidus after birth.

Recent advance in endocrine pathology in 2002. Hypophysis. A case of growth hormone producing hypophyseal adenoma manifested by exhibiting diabetes insipidus after birth.

Accession number;02A0594741

Title;Recent advance in endocrine pathology in 2002. Hypophysis. A case of growth hormone producing hypophyseal adenoma manifested by exhibiting diabetes insipidus after birth.

Author; OYAMA KEN'ICHI (Nippon Med. Sch.) WADA SEIKI (Saitama Med. Coll., Igakubu) SATO SHUN (Nippon Med. Sch.) WATANABE KUNIHIRO (Nippon Med. Sch.) TAMAOKI TOMONORI (Nippon Med. Sch.) SANNO NAOKO (Nippon Med. Sch.) KATAYAMA SHIGEHIRO (Saitama Med. Coll., Igakubu) OSAMURA YOSHIYUKI (Tokai Univ., Sch. of Med.) TERAMOTO AKIRA (Nippon Med. Sch.)

Journal Title;Clinical Endocrinology

Journal Code:Z0648A

ISSN:0045-7167

VOL.50;NO.;PAGE.16-20(2002)

Figure&Table&Reference;FIG.4, REF.6

Pub. Country;Japan

Language;Japanese

Abstract;A case (32-year-old woman) of growth hormone producing hypophyseal adenoma manifested by exhibiting diabetes insipidus after birth is reported. From the clinical course, diagnostic imaging findings and histopathology findings, the complication of the lymphocytic hypophysitis was presumed. The main inflammation is indicated to be in the hypophyseal stalk - posterior lobe. Adenoma cells were positive for GH and PRL in the immunohistochemistry staining, and the involvement of the autoimmune mechanism was inferred. Physical signs as acromegaly were poor, and comparatively early disease states were considered.

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