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Accession number;02A0421400
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| Title;Bioorganic Studies on DNA and Design of DNA Targeting Molecules. |
| Author;
SAITO ISAO
(Kyoto Univ., Grad. Sch.)
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Journal Title;Nippon Kagakkai Koen Yokoshu
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Journal Code:S0493A
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ISSN:0285-7626
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VOL.81st;NO.1;PAGE.A.3(2002)
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| Figure&Table&Reference; |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Following topics on chemical genomics will be presented. These include, 1) design and synthesis of tailor-made DNA alkylating agents possessing anticancer activity, 2) molecular design of DNA mismatch recognition molecules and its use for SNPs detection, 3) development of new methods for light-triggered gene manipulation, 4) mechanistic studies of DNA-mediated electron transfer process, 5) design of artificial DNAs of novel functions such as parallel DNA, 6) mapping of HOMO of duplex DNA. (author abst.) |
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