Two Children Whose Asthma Was Influenced By Exposure to Residential Formaldehyde.

Accession number;02A0492517
Title;Two Children Whose Asthma Was Influenced By Exposure to Residential Formaldehyde.
Author; KISHIDA MASARU (Toho Univ., Ohashi Hosp.) SUZUKI ITSUO (Toho Univ., Ohashi Hosp.) NAKAZONO HIROYUKI (Toho Univ., Ohashi Hosp.) IZAWA MASAKO (Toho Univ., Ohashi Hosp.) OKADA MARI (Toho Univ., Ohashi Hosp.)
Journal Title;Journal of the Japan Pediatric Society
Journal Code:F0896A
ISSN:0001-6543
VOL.106;NO.5;PAGE.680-683(2002)
Figure&Table&Reference;FIG.1, TBL.1, REF.19
Pub. Country;Japan
Language;Japanese
Abstract;We describe two asthma children; a one-year-old girl whose asthma is doe to formaldehyde and a 12-year-old boy who suffered from exacerbation of the problem due to formaldehyde exposure in newly constructed residence. Though they have no specific IgE antibodies against formaldehyde, their symptoms were improved by emission of formaldehyde. Formaldehyde is known to cause irritation of the mucous membranes, to lead to a cell-mediated and antibody-mediated allergic response such as haptens, and to enhance allergic sensitization and allergic inflammation. Therefore, formaldehyde brings about the appearance and aggravation fo allergic diseases, which include bronchial asthma. But, the action mechanism and concentration are not clear, as well as the VOCs. You must give careful consideration to indoor VOCs as well when appearance or exacerbation of asthma is brought about in the new construction or reform of a residence. Though removal of the source of occurrence is the first step, ventilation and use of an air cleaner to remove the chemical material are thought to be useful as the next best methods. (author abst.)