Solution and Solid-Phase Synthesis of Chiral Fluoro Amino Compounds, Peptides and Mimetics.

Accession number;02A0620428
Title;Solution and Solid-Phase Synthesis of Chiral Fluoro Amino Compounds, Peptides and Mimetics.
Author; BRAVO P (Politecnico Di Milano, Milano, Ita) VOLONTERIO A (Politecnico Di Milano, Milano, Ita) ZANDA M (Politecnico Di Milano, Milano, Ita)
Journal Title;Fusso Kagaku Toronkai Koen Yoshishu
Journal Code:F0135B
ISSN:
VOL.25th;NO.;PAGE.77-78(2001)
Figure&Table&Reference;
Pub. Country;Japan
Language;English
Abstract;Aryl beta-imino/enamino-gamma-fluorosubstituted propyl sulfoxides and the corresponding reduced amino derivatives are utilized as chiral templates in the asymmetric synthesis of title compounds. Improvements achieved in the control of diastereoselection during the preparation of the templates by changing the aryl moiety at sulfur and the substituent on the nitrogen atom will be reported. (author abst.)