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Accession number;02A0514990
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| Title;Neuroimagings for Acute Ischemic Stroke. |
| Author;
NAKAGAWARA JOJI
(Nakamurakinenbyoin Noshinkeigeka Nosotchushinryobu)
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Journal Title;Prog Med
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Journal Code:F0664B
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ISSN:0287-3648
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VOL.22;NO.5;PAGE.1127-1131(2002)
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| Figure&Table&Reference;FIG.4, TBL.1, REF.12 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Neuroimagings for acute ischemic stroke should be performed in diagnostic process to define clinical category of ischemic stroke. Especially, identification of ischemic penumbra and core using neuroimagings is essential for patient selection of thrombolytic therapy for acute ischemic stroke. Early ischemic CT sign is defined as unclearness or disappearance of the lentiform nucleus, sylvian fissure, border of cortico-medullary junction or cortical sulci. MRI seems to be superior to CT for identifying acute cerebral infarction; however early ischemic changes cannot be identified without diffusion-weighted imaging (DWI). Perfusion-weighted imaging (PWI) using intravenous injection of Ga-DTPA could be additional information to evaluate severity of acute cerebral ischemia. Ischemic penumbra could be detected by diffusion-perfusion mismatch. SPECT could measure residual cerebral blood flow (CBF) in both ischemic penumbra and core. Tissue viability in acute cerebral ischemia seems to depend on not only residual CBF but also time from stroke onset. Hereafter therapeutic guidelines for acute ischemic stroke have been confirmed, diagnostic guideline should be established for neuroimagings of acute ischemic stroke. (author abst.) |
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