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Accession number;02A0515005
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| Title;A New Strategy for Acute Brain Infarction. |
| Author;
KOBAYASHI SHOTAI
(Shimane Med. Univ., Igakubu)
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Journal Title;Prog Med
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Journal Code:F0664B
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ISSN:0287-3648
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VOL.22;NO.5;PAGE.1123-1227(2002)
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| Figure&Table&Reference;FIG.5, REF.6 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;A new strategy for acute brain infarction should be an intravenous thrombolytic therapy. Japan standard stroke registry study (JSSRS) group (Chief investigator: S. Kobayashi) showed significant increase in the ratio of atherothrombotic and cardiogenic embolism in ischemic brain infarction than 20 years ago (atherothrombotic 28.7%, cardiogenic embolism 26.6%. lacuna 27.8%) (Fig. 1). About half of the ischemic stroke patients admitted hospital within 6 hours. The incidence of atrial fibrillation significantly increased with aging (Fig. 2). According to JSSRS data, thrombolytic therapy was performed in 3.9% of whole cerebral infarction (n = 5,874), and 15.5% in the patients with moderate severity (NIHSS 6-29) who admitted within 3 hours from stroke onset (n = 665). The thrombolytic therapy group showed significant improvement in modified Rankin scale at discharge than those without thrombolytic therapy in JSSRS analysis. Acute stroke databank is valuable for analysis of stroke therapy and planning of the strategy for new therapy. Global evaluation is necessary to compare the effect of therapy in acute stroke among hospitals and countries. (author abst.) |
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