Ring-Fluorinated Quinoline and Isoquinoline Synthesis: Intramolecular Substitution Reaction of o-Substituted gem-Difluorostyrenes.
|
Accession number;02A0620432
|
| Title;Ring-Fluorinated Quinoline and Isoquinoline Synthesis: Intramolecular Substitution Reaction of o-Substituted gem-Difluorostyrenes. |
| Author;
ICHIKAWA J
(Univ. Tokyo, Tokyo, Jpn)
WADA Y
(Univ. Tokyo, Tokyo, Jpn)
MORI T
(Univ. Tokyo, Tokyo, Jpn)
MIHARA J
(Univ. Tokyo, Tokyo, Jpn)
|
Journal Title;Fusso Kagaku Toronkai Koen Yoshishu
|
Journal Code:F0135B
|
ISSN:
|
|
VOL.25th;NO.;PAGE.84-85(2001)
|
| Figure&Table&Reference; |
| Pub. Country;Japan |
| Language;English |
| Abstract;Starting from gem-difluorostyrenes bearing an ortho substituent such as amino, isocyano, cyano, formyl, and aminomethyl groups, intramolecular substitution for the vinylic fluorines readily proceed via addition-elimination processes with sp3 or sp2 nitrogen or carbon nucleophiles generated in situ at the ortho position. Desired ring-fluorinated quinoline and isoquinoline derivatives are obtained in high yields. (author abst.) |
|
|
|
Related Articles;
|
|
