Terpenoid constituents of Alismatis Rhizoma-Structure, biological activity, and chemical change of terpenoids during processing.

Accession number;02A0774018
Title;Terpenoid constituents of Alismatis Rhizoma-Structure, biological activity, and chemical change of terpenoids during processing.
Author; YOSHIKAWA MASAYUKI (Kyoto Pharmaceutical Univ., JPN) MATSUDA HISASHI (Kyoto Pharmaceutical Univ., JPN)
Journal Title;Journal of Traditional Medicines
Journal Code:Y0941A
ISSN:1340-6302
VOL.19;NO.4;PAGE.119-128(2002)
Figure&Table&Reference;FIG.8, TBL.5, REF.27
Pub. Country;Japan
Language;Japanese
Abstract;The dried rhizome of the aquatic plant Alisma orientale JUZEP. (Alismataceae) has been used as a Chinese natural medicine, Alismatis Rhizoma, which is prescribed for diuretic and anti-inflammatory purposes, and treatment of thirst in various Kampo medicinal preparations. In recent years, Chinese Alismatis Rhizoma has been imported and commonly used in Kampo medicine, due to the poor supply of Japanese Alismatis Rhizoma. In Japan, Chinese Alismatis Rhizoma is classified into two types named in Japanese as "Sentaku" (from Szechwan Province) and "Kentaku" (from Fukien Province) according to their regions of origin. This article deals with our recent chemical and pharmacological studies, which include the structures and biological activities on the sesquiterpene and triterpene constituents from Sentaku, Kentaku, and Japanese Alismatis Rhizoma. In addition, the changes of the terpenoid constituents during the drying process of the rhizome of Alisma orientale were investigated using quantitative method by HPLC and several bioactive sesquiterpenes and triterpenes were found to be artificially formed during the drying process. (author abst.)