The two cases of hepatocellular carcinoma associated with cyproterone acetate.
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Accession number;02A0654454
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| Title;The two cases of hepatocellular carcinoma associated with cyproterone acetate. |
| Author;
KOMURA MAKOTO
(National Children's Hospital, JPN)
HONNA TOSHIRO
(National Children's Hospital, JPN)
TANAKA KIYOSHI
(National Children's Hospital, JPN)
MATSUOKA KENTARO
(National Children's Hospital, JPN)
MIYAUCHI JUN
(National Children's Hospital, JPN)
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Journal Title;Japanese Journal of Pediatric Oncology
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Journal Code:X0797A
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ISSN:0389-4525
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VOL.39;NO.1;PAGE.61-64(2002)
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| Figure&Table&Reference;FIG.2, TBL.2, REF.12 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Two cases (28- and 26-year-old females) of hepatocellular carcinoma that are suspected to be related to the administration of cyproterone acetate, a medicine for precocious puberty used generally in our country in 1980s, were experienced. Cyproterone acetate had been administered in large amounts, reaching 1,160g and 916g in total amounts. APF, a tumor marker for the hepatocellular carcinoma, showed a high value at the diagnosis, but was normalized after the excision of the liver. In one of the cases, 9 years have past after the operation without a recurrence, but in the other case, an internal recurrence was recognized after a year and 5 months, and a tumor extraction was performed. |
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