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Accession number;03A0040612
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| Title;Structure of the bacterial RNA polymerase holoenzyme. |
| Author;
SEKINE SHUN'ICHI
(Inst. Physical and Chemical Res., JPN)
VASSYLYEV D G
(Inst. Physical and Chemical Res., JPN)
YOKOYAMA SHIGEYUKI
(Inst. Physical and Chemical Res., JPN)
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Journal Title;Protein, Nucleic Acid and Enzyme
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Journal Code:F0325A
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ISSN:0039-9450
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VOL.48;NO.1;PAGE.1-8(2003)
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| Figure&Table&Reference;FIG.8, REF.27 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;RNA polymerase is the enzyme to control transcription process of DNA's nucleotide sequences to RNA. In the case of procaryotes, core enzyme as a central part of RNA polymerase is bound to .SIGMA. factor, a transcription initiator,and can initiate transcription for the first time after becoming a holoenzyme.High-resolution crystal structure of holoenzyme as a minimum unit required for transcription initiation can open the gate to understand the complicated mechanisms of transcription initiation from the aspect of 3D structures. |
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