Effect of Late Evening Snack Composed of a Special Amino Acid Preparation on Liver Cirrhosis.
|
Accession number;03A0059362
|
| Title;Effect of Late Evening Snack Composed of a Special Amino Acid Preparation on Liver Cirrhosis. |
| Author;
KOREEDA CHIZU
(Kansai Med. Univ.)
SATO MASAHIRO
(Kansai Med. Univ.)
MIZUNO TAKAKO
(Kansai Med. Univ.)
HA-KAWA S
(Kansai Med. Univ.)
|
Journal Title;Japanese Pharmacology & Therapeutics
|
Journal Code:Z0947A
|
ISSN:0386-3603
|
|
VOL.30;NO.Suppl.2;PAGE.S.307-S.312(2002)
|
| Figure&Table&Reference;FIG.4, REF.18 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Objective: The Late Evening Snack (LES), composed of a special amino acid preparation, has been receiving close attention as a means of improving the hepatic malfunction derived from overnight starvation of cirrhotic patients. The present study was undertaken to examine the effects of this snack on hepatic reserves and nutrient metabolism. Subjects and Methods: Six patients with liver cirrhosis, including one patient who had liver cancer, one Child grade A and five Child grade took LES (two pack of Aminoleban EN a day). Indicators of liver function measured were asialoscintigraphic Rmax (indicator of total liver receptors), asialoscintigraphic imaging grade, ICG, PT, T-bil, Alb, NH3 and BTR (molar ratio of branched chain amino acids to tyrosine). Results: Rmax improved by 5% or more in four cases, and by 29% on average of all cases after the start of treatment. The mean Rmax tended to improve after treatment (p = 0.1). BTR improved by 5% or more in three cases and by 3.5% on average but not significantly. ICG, PT and NH3 showed no improvement. T-bil decreased by 0.1 mg/dL on average. Alb improved in five of the six cases, and rose by 0.2 g/dL on average. Conclusion: The results of this study suggest that LES with Aminoleban EN can improve the hepatic malfunction due to overnight starvation of patients with liver cirrhosis, and provides a useful means of nutritional therapy in improving the hepatic reserves of cirrhotic patients. (author abst.) |
|
|
|
Related Articles;
|
|
