Niacin Availability in Instant Coffee to Rats.

Accession number;03A0096356
Title;Niacin Availability in Instant Coffee to Rats.
Author; FUKUWATARI TSUTOMU (Univ. Shiga Prefecture, School of Human Cultures, JPN) SAITO CHIE (Univ. Shiga Prefecture, School of Human Cultures, JPN) SASAKI RYUZO (Univ. Shiga Prefecture, School of Human Cultures, JPN) SHIBATA KATSUMI (Univ. Shiga Prefecture, School of Human Cultures, JPN)
Journal Title;Journal of Home Economics of Japan
Journal Code:F0763A
ISSN:0913-5227
VOL.54;NO.1;PAGE.77-82(2003)
Figure&Table&Reference;FIG.4, TBL.1, REF.17
Pub. Country;Japan
Language;Japanese
Abstract;The bioavailability of niacin in instant coffee was investigated by using weaning rats fed with a niacin-free and tryptophan-limited diet. The growth rate was significantly improved by supplementing instant coffee powder to the niacin-free anti tryptophan-limited diet, and the niacin coenzyme levels, NAD and NADP, in the blood and liver were significantly increased. The urinary excretion of nicotinamide and its catabolic metabolites, N1-methylnicotinamide, N1-methyl-2-pyridone-5-carboxamide, and N1-methyl-4-pyridone-3-carboxamide, were significantly increased by the addition of instant coffee powder. These results suggest that instant coffee contains very useful precursors of pyridine nucleotide coenzyrnes to mammals. (author abst.)
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