Science Links Japan | The First Example of .ALPHA.-Thiomagnesiums Generated from Dithioacetal Monoxides with Grignard Reagent; Their Properties and Some Synthetic Applications.

The First Example of .ALPHA.-Thiomagnesiums Generated from Dithioacetal Monoxides with Grignard Reagent; Their Properties and Some Synthetic Applications.

Accession number;03A0096296

Title;The First Example of .ALPHA.-Thiomagnesiums Generated from Dithioacetal Monoxides with Grignard Reagent; Their Properties and Some Synthetic Applications.

Author; SATOH T (Tokyo Univ. Sci., Tokyo, Jpn) AKITA K (Tokyo Univ. Sci., Tokyo, Jpn)

Journal Title;Chem Pharm Bull

Journal Code:G0504A

ISSN:0009-2363

VOL.51;NO.2;PAGE.181-186(2003)

Figure&Table&Reference;TBL.3, REF.25

Pub. Country;Japan

Language;English

Abstract;Dithioacetal monoxides were synthesized from aldehydes and cyclohexanone, and reaction of the dithioacetal monoxides with Grignard reagents was investigated. The dithioacetal monoxide synthesized from alkylaldehyde and 4-chlorobenzenethiol reacted with i-PrMgCl to afford the desired .ALPHA.-thiomagnesium in high yield. The generated .ALPHA.-thiomagnesium was found to be stable at room temperature and to be useful in organic synthesis. In contrast to this, the dithioacetal monoxides derived from benzaldehyde and cyclohexanone did not give satisfactory results. (author abst.)

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