O-Demethylation and Sulfation of 7-Methoxylated Flavanones by Cunninghamella elegans.
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Accession number;03A0096302
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| Title;O-Demethylation and Sulfation of 7-Methoxylated Flavanones by Cunninghamella elegans. |
| Author;
IBRAHIM A-R S
(Tanta Univ., Tanta, Egy)
GALAL A M
(Cairo Univ., Cairo, Egy)
AHMED M S
(King Saud Univ., Riyadh, Sau)
MOSSA G S
(King Saud Univ., Riyadh, Sau)
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Journal Title;Chem Pharm Bull
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Journal Code:G0504A
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ISSN:0009-2363
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VOL.51;NO.2;PAGE.203-206(2003)
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| Figure&Table&Reference;TBL.2, REF.23 |
| Pub. Country;Japan |
| Language;English |
| Abstract;Metabolism of 7-O-methylnaringenin (sakuranetin) by Cunninghamella elegans NRRL 1392 yielded naringenin and naringenin-4'-sulfate. C. elegans also converted 5,3',4'-trihydroxy-7-methoxyflavanone into eriodictyol-4'-sulfate. Furthermore, incubation of 5,4'-dihydroxy-7,3'-dimethoxyflavanone with the same fungus gave homoeriodictyol (5,7,4'-trihydroxy-3'-methoxyflavanone) and homoeriodicytol-7-sulfate. The structures of the new metabolites were established by spectral analysis including 2D-NMR, HR-ESI-FT-MS beside hydrolysis by acid. (author abst.) |
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