Canine Bcl-xL Gene and Its Expression in Tumor Cell Lines.

Accession number;03A0102018
Title;Canine Bcl-xL Gene and Its Expression in Tumor Cell Lines.
Author; SANO J (Nihon Univ. School Of Veterinary Medicine, Kanagawa, Jpn) OGUMA K (Nihon Univ. School Of Veterinary Medicine, Kanagawa, Jpn) KANO R (Nihon Univ. School Of Veterinary Medicine, Kanagawa, Jpn) HASEGAWA A (Nihon Univ. School Of Veterinary Medicine, Kanagawa, Jpn)
Journal Title;J Vet Med Sci
Journal Code:F0905A
ISSN:0916-7250
VOL.65;NO.1;PAGE.149-151(2003)
Figure&Table&Reference;TBL.2, REF.28
Pub. Country;Japan
Language;English
Abstract;The canine Bcl-xL gene was cloned and sequenced. Canine Bcl-xL cDNA clone was 1252 bp in length, and encoded 233 deduced amino acides. The predicted canine Bcl-xL amino acid sequence shared 99.6%, 97.0%, 97.9%, 98.7% and 98.3% homology with that of human, mouse, rat, sheep and pig Bcl-xL, respectively. RT-PCR analysis revealed that canine Bcl-xL mRNA was constitutively expressed in CL-1 (canine lymphoma) and GL-1 (canine B cell leukemia) cell lines. (author abst.)
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