Mechanisms of vesicle transport in polarized cells orchestrated by Rab GTPase.
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Accession number;03A0078707
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| Title;Mechanisms of vesicle transport in polarized cells orchestrated by Rab GTPase. |
| Author;
KAJIHO HIROAKI
(Univ. Tokyo, Graduate School of Parmaceutical Sciences, JPN)
SAITO KOTA
(Univ. Tokyo, Graduate School of Parmaceutical Sciences, JPN)
ARAKI YASUHIRO
(Univ. Tokyo, Graduate School of Parmaceutical Sciences, JPN)
KATADA TOSHIAKI
(Univ. Tokyo, Graduate School of Parmaceutical Sciences, JPN)
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Journal Title;Protein, Nucleic Acid and Enzyme
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Journal Code:F0325A
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ISSN:0039-9450
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VOL.48;NO.2;PAGE.133-139(2003)
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| Figure&Table&Reference;FIG.4, TBL.1, REF.50 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Though epithelial cells cover the surface of organs and tissues, and control materfial exchanges with external worlds by specific barrier functions, in these cells polarization of their cell surfaces and vesicle transport pathways is observable. Low molecular weight G proteins such as Rab, Rho, Rac, and Cdc42 intervene in maintenance and control of vesicle transports with polarity in epithelial cells. This article introduces recent knowledges by focusing on the role of Rab family acting in vesicle transports of polarity cells, and by including knowledges on Rab5, of which activation mechanism and binding protein are being analyzed in detail among Rab family. |
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