Studies on the Marker Compounds for Standardization of Traditional Chinese Medicine "Polyporus Scierotium".

Accession number;03A0096360
Title;Studies on the Marker Compounds for Standardization of Traditional Chinese Medicine "Polyporus Scierotium".
Author; YUAN D (Shenyang Pharmaceutical Univ., Shenyang, Chn) YAMAMOTO KEIICHI (Kanebo Ltd., JPN) BI K (Shenyang Pharmaceutical Univ., Shenyang, Chn) ZHANG P (Shenyang Pharmaceutical Univ., Shenyang, Chn) LIU F (Shenyang Pharmaceutical Univ., Shenyang, Chn) KANO YOSHIHIRO (Hokkaido Inst. of Pharm. Sci.)
Journal Title;Journal of the Pharmaceutical Society of Japan
Journal Code:F0508A
ISSN:0031-6903
VOL.123;NO.2;PAGE.53-62(2003)
Figure&Table&Reference;FIG.4, TBL.5, REF.27
Pub. Country;Japan
Language;Japanese
Abstract;Natural products have been used for healthcare and pharmacotherapy. Because difficulties in quality control affect their production, processing, and marketing, it is necessary to establish adequate marker compounds for their effective application. Ergosta-4,6,8(14),22-tetraen-3-one (I) was studied in the screening of the marker compounds for the standardization of Polyporus Sclerotium, which has the advantage of easy qualitative and quantitative analysis because of its fluorescence. Its applicability in the standardization of Polyporus Sclerotium is discussed based on comparative studies of 30 crude samples of Polyporus Sclerotium and some other fungi herbs using TLC and HPLC analysis with lit as the marker compound, as well as its chemical synthesis. (author abst.)
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