Effects of Administration of Bifidobacteria on Fecal Microflora and Clinical Symptoms in Infants with Atopic Dermatitis.
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Accession number;03A0141509
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| Title;Effects of Administration of Bifidobacteria on Fecal Microflora and Clinical Symptoms in Infants with Atopic Dermatitis. |
| Author;
HATTORI KAZUHIRO
(Kansaiidai Koribyoin Shonika)
YAMAMOTO AKEMI
(Kansai Med. Univ.)
SASAI MISA
(Kansai Med. Univ.)
TANIUCHI SHOICHIRO
(Kansai Med. Univ.)
KOJIMA TAKATSUGU
(Kansai Med. Univ.)
KOBAYASHI YONOSUKE
(Kansai Med. Univ.)
IWAMOTO HIROSHI
(Morinaga Milk Ind. Co., Ltd., Nutr. Sci. Lab., JPN)
NAMBA KYOKO
(Morinaga Milk Ind. Co., Ltd., Nutr. Sci. Lab., JPN)
YAESHIMA TOMOKO
(Morinaga Milk Ind. Co., Ltd., Nutr. Sci. Lab., JPN)
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Journal Title;Japanese Journal of Allergology
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Journal Code:Z0644A
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ISSN:0021-4884
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VOL.52;NO.1;PAGE.20-30(2003)
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| Figure&Table&Reference;FIG.5, TBL.4, REF.27 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Fifteen children with atopic dermatitis who had Bifidobacterium-deficient microflora were selected for this study. Eight subjects in the bifidobacteria-administered group were given oral administration of lyophilized bifidobacteria (Bifidobacterium breve M-16V strain). The changes in fecal microflora and clinical symptoms were compared with the control group. In the bifidobacteria-administered group, the proportion of Bifidobacterium in the fecal microflora was increased (P=0.0173) and the proportion of aerobic bacteria was decreased (P=0.0499) after 1 month of administration. Furthermore, significant improvement of allergic symptoms (P=0.0176 in cutaneous symptom score, P=0.0117 in total allergic score) was also observed in the bifidobacteria-administered group. The tendency of allergic symptom improvement in the bifidobacteria-administered group was remarkable compared with the control group; however there was no correlation between changes in fecal microflora and allergic symptoms. (author abst.) |
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