Effectiveness of ramosetron hydrochloride for pediatric cancer patients.
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Accession number;02A0934760
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| Title;Effectiveness of ramosetron hydrochloride for pediatric cancer patients. |
| Author;
UEDA HARUO
(Hiroshima Univ., Sch. of Med.)
MIYAGAWA SHIN'ICHIRO
(Hiroshima Univ., Sch. of Med.)
TAKAMOTO SATOSHI
(Hiroshima Univ., Sch. of Med.)
HANEHARA MASAKAZU
(Hiroshima Univ., Sch. of Med.)
SERA YASUHIKO
(Hiroshima Univ., Sch. of Med.)
SATO TAKASHI
(Hiroshima Univ., Sch. of Med.)
NISHIMURA SHIN'ICHIRO
(Hiroshima Univ., Sch. of Med.)
UEDA KAZUHIRO
(Hiroshima Univ., Sch. of Med.)
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Journal Title;Japanese Journal of Pediatric Oncology
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Journal Code:X0797A
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ISSN:0389-4525
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VOL.39;NO.2;PAGE.182-186(2002)
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| Figure&Table&Reference;FIG.7, TBL.2, REF.9 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Regarding nausea and vomiting caused by antineoplastics( cisplatin, cytarabine, ifomide, cyclophosphamide, methotrexate and actinomycin-D), effectiveness of the titled drug(RAM)(based on each age group, days of chemotherapy and frequency of a course) were studied. RAM(5.MU.g/kg) was intravenously administered to 14 cases(1-15 years old) just before antineoplastics. When nausea and vomiting were intense after the administration, RAM was additionaly given. Questionnairing was done on the first and fifth day of chemotherapy. Nausea was in a slight degree as a whole and vomiting occurred with low frequency. The state at meal and general condition did not become worse, and no adverse effect occurred. Therefore RAM was considered to be safe and effective. Both nausea and vomiting were slight in babyhood and tended to intensify as the course was repeated. These are probably attributed to participation of expectation vomiting as an addtional factor. |
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