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Accession number;02A0934761
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| Title;Effectivenss of cisplatin/vincristine combination chemotherapy for hypothalamic/chiasmatic pilocytic astrocytoma in very young children. |
| Author;
SAWAMURA YUTAKA
(Hokkaido Univ.)
KATO TSUTOMU
(Hokkaido Univ.)
MAYUZUMI HIDEYASU
(Hokkaido Univ.)
IKEDA JUN
(Hokkaido Univ.)
AOYAMA HIDEFUMI
(Hokkaido Univ., Sch. of Med.)
SHIRATO HIROKI
(Hokkaido Univ., Sch. of Med.)
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Journal Title;Japanese Journal of Pediatric Oncology
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Journal Code:X0797A
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ISSN:0389-4525
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VOL.39;NO.2;PAGE.187-191(2002)
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| Figure&Table&Reference;FIG.2, TBL.1, REF.16 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;6 cases(infants and children of 5 months-5 years old) with the titled disease were treated with chemotherapy(CDDP/VCR). One course included CDDP 20mg/sq.m/day(the 1st-5th day) and VCR1 4mg/sq.m/day(the 1st, 8th and 15th day) and was repeated 4 times every 4 weeks. Then, from the 5th course, according to the state of tumor reduction, prolonged administration of 6-8 courses was done. A month after finishing the chemotherapy, there were 4 cases with partial response and 2 cases with disease stabilized, having tumor reduced slightly every end of one course. After treatment, regrowth was recognized in 4 cases. Then the 4 cases received radiotherapy or extirpation as salvage therapy when they were more than 4 years old. On their last visits, all cases existed with visual function to make their daily life available. |
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