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Accession number;02A0934772
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| Title;A successful BMT from the same donor for EBV-associated Burkitt Lymphoma after living-related liver transplantation during atypical post-transfusion GVHD. |
| Author;
ISHIKO YUKA
(Kanagawa Children's Medical Center, JPN)
SUZUKI TETSUOMI
(Kanagawa Children's Medical Center, JPN)
TOYODA YASUNORI
(Kanagawa Children's Medical Center, JPN)
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Journal Title;Japanese Journal of Pediatric Oncology
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Journal Code:X0797A
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ISSN:0389-4525
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VOL.39;NO.2;PAGE.239-243(2002)
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| Figure&Table&Reference;FIG.3, TBL.1, REF.9 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;The case(a male infant) received living liver transplantation from his father at age of 1 years and 7 months due to congenital biliary atresia. Though FK506 was orally given since then, he was taken to our hospital due to abdominal distension and vomiting. He was diagnosed as Burkitt lymphoma, Stage IV associated with EBV after the transplantation. 1 course of treatment according to TCCSG NHL B96-04 protocol Group D was done to result in remission with persistent pancytopenia of unknown etiology. HLA of the patient's myeloid cell was a donor-type. Being in his immunosuppressive condition due to immunosuppressive agent and chemotherapy, HLAs of the patient and his father were in the same direction of graft rejection and there was inconsistency in 1 locus of GVHD direction. Thus the donor's stem cell derived from the transplanted liver was implanted to result in onset of post-transfusion GVHD-like symptom. Hemopoietic function was recovered by bone marrow transplantation from his father as the donor, and there was no complication to result in improved general condition. |
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