Acute Radial Artery Occlusion in a Diabetic Woman with Paroxysmal Atrial Fibrillation That Became Chronic and Caused Cerebral Infarction.

Accession number;03A0149371
Title;Acute Radial Artery Occlusion in a Diabetic Woman with Paroxysmal Atrial Fibrillation That Became Chronic and Caused Cerebral Infarction.
Author; HAYAKAWA MICHIKO (Hyogokensogorihabiriteshonse Rihabiriteshonchuobyoin Naika) IWAHASHI MASANORI (Hyogokensogorihabiriteshonse Rihabiriteshonchuobyoin Junkankika) KATO JUN'ICHI (Hyogokensogorihabiriteshonse Rihabiriteshonchuobyoin Naika) TANIZAKI TOSHIRO (Hyogokensogorihabiriteshonse Rihabiriteshonchuobyoin Junkankika) IKEDA YOSHINORI (Hyogokensogorihabiriteshonse Rihabiriteshonchuobyoin Naika) TAKADA MASAMI (Hyogokensogorihabiriteshonse Rihabiriteshonchuobyoin Naika) ISHIHARA KENZO (Hyogokensogorihabiriteshonse Rihabiriteshonchuobyoin Naika) KAZUMI TSUTOMU (Hyogokensogorihabiriteshonse Rihabiriteshonchuobyoin Naika)
Journal Title;Journal of the Japan Diabetic Society
Journal Code:Z0279B
ISSN:0021-437X
VOL.46;NO.1;PAGE.23-27(2003)
Figure&Table&Reference;FIG.1, TBL.1, REF.12
Pub. Country;Japan
Language;Japanese
Abstract;A 75-year-old diabetic woman with arterial hypertension admitted for 1.5 hours of pain and coldness in her right forearm was found in arteriography to have a completely occluded radial artery, which was treated with direct injection of a thrombolytic agent into the brachial artery. Signs and symptoms of acute radial artery obstruction disappeared immediately after injection. After 15 days, repeated arteriography failed to show atherosclerotic changes in her right radial artery. Routine electrocardiographic (ECG) monitoring showed no abnormalities except for a pathological Q wave in leads V1-3. Myocardial perfusion scintigraphy showed a septal defect and UCG showed an enlarged left atrium but no abnormal wall motion. Frequent Holter monitoring showed asymptomatic paroxysmal atrial fibrillation (PAf). Increased risk of nonvalvular atrial fibrillation is reported to be associated with a history of coronary disease, hypertension, diabetes and an enlarged left atrium. We concluded that her arterial occlusion was due to PAf. Some 18 months after this episode, her PAf developed into CM, which caused a cerebral embolism even though she was treated with warfarin. Because PAf has been reported to carry a risk of thromboembolism, which approaches that of established chronic atrial fibrillation in those with heart disease, we suggest that diabetic patients with many risk factors be given Holter monitoring even if their ECGs are normal. (author abst.)