Clinical Study on Five Surgical Cases of Thymic Carcinoma.
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Accession number;03A0117069
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| Title;Clinical Study on Five Surgical Cases of Thymic Carcinoma. |
| Author;
OSAKI TOSHIHIRO
(Kitakyushu Munic. Med. Center)
NAGASHIMA AKIRA
(Kitakyushu Munic. Med. Center)
YOSHIMATSU TAKASHI
(Kitakyushu Munic. Med. Center)
TASHIMA YUKO
(Kitakyushu Munic. Med. Center)
YASUMOTO KOSEI
(Univ. of Occup. and Environ. Health)
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Journal Title;Journal of Japan Surgical Association
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Journal Code:Z0103A
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ISSN:1345-2843
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VOL.64;NO.1;PAGE.55-59(2003)
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| Figure&Table&Reference;FIG.2, TBL.1, REF.12 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Five patients with surgically resected thymic carcinoma in the hospital were reviewed clinically. There were two men and three women: their ages ranged from 39 to 68 years. The pathologic subtypes of thymic carcinoma included one basaloid carcinoma, three undifferentiated/anaplastic carcinomas, and one poorly differentiated squamous cell carcinoma. Three patients had stage III disease, one had stage IVa, and one had stage IVb. The patient with basaloid carcinoma, low-grade histology of thymic carcinoma, underwent a complete resection and is alive without recurrence 13 months after the surgery. Of four patients with undifferentiated/anaplastic carcinoma or poorly differentiated squamous cell carcinoma, high-grade histology of thymic carcinoma, three patients underwent a complete resection and two of them received radiotherapy. Two patients are alive without recurrence 36 and 80 months after the surgery, respectively. The other patient suffered from local recurrence and underwent a surgical resection for the relapse sites 27 months after the surgery. Following the second surgery, she received systemic chemotherapy and died 61 months after the initial surgery. The remaining patient of high-grade histology underwent an incomplete resection and received postoperative chemotherapy, however, she died 28 months after the surgery. Our data show that complete resection and adjuvant therapies may yield long-term survival even for the patients with thymic carcinoma of high-grade histology such as undifferentiated/anaplastic carcinoma. (author abst.) |
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