A Study of Pathology and Clinical Findings in Cervical Lymph Node Biopsies.

Accession number;03A0140978
Title;A Study of Pathology and Clinical Findings in Cervical Lymph Node Biopsies.
Author; ASAKAWA TAKESHI (Tachikawabyoin Jibiinkoka) YOSHIDA SHIN'YA (Tachikawabyoin Jibiinkoka) YOSHIKAWA TAKUMA (Tachikawabyoin Jibiinkoka) KISHIDA SATORU (Tachikawabyoin Jibiinkoka)
Journal Title;Journal of the Japan Broncho-Esophagological Society
Journal Code:Z0674A
ISSN:0029-0645
VOL.54;NO.1;PAGE.32-37(2003)
Figure&Table&Reference;FIG.1, TBL.4, REF.13
Pub. Country;Japan
Language;Japanese
Abstract;We investigated the pathology, age groups, blood test, CT image, isotope findings and fine-needle aspiration biopsy (FNAB) diagnosis in 92 cervical lymph node biopsies. There were 31 cases of benign causes and 61 cases of malignant cases. 18 patients had been treated for malignant disease previously. Of these 18, 17 had had a recurrence of a previous malignant disease. Eleven of the 15 cases that showed an enhancement in the CT examination were malignant. Sensitivity and specificity for malignant etiology in the gallium isotope examination were 91.4% and 37.5%. The hot spot for scintigraphy with 67Ga was helpful for diagnosis of malignancy. In a total of 8 cases of malignant lymphoma and metastatic lymphoepithelial carcinoma, 5 cases were diagnosed as Class I or II by fine-needle aspiration biopsy. However, there was a hot spot for scintigraphy with 67Ga in these 5 cases. Therefore, we concluded that the indications of operation in cervical lymph node biopsy are the following. 1) elderly patients with lymphadenopathy that have shown no spontaneous regression for a long time. 2) patients who have been treated for malignant disease previously except for class IV or V. 3) patients who were found to have an enhancement in their CT besides a hot spot for scintigraphy. 4) suspicion of malignant lymphoma, a hot spot for scintigraphy but in Class I or II. We also investigated 9 cases -4 men and 5 wowen aged 13-34 years -with necrotizing lymphadenitis that were correctly diagnosed by biopsy. Antibiotics were not effective in all cases. These patients were improving by taking prednisone after their biopsy. We considered a biopsy necessary in cases where it is difficult to distinguish malignant lymphoma from the effects of prednisone. (author abst.)
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